| Medications such as Prednisolone, Prednisone
and Dexamethasone are used to treat a variety of disorders,
but unfortunatey due to bitter taste, are very difficult for
young patients to swallow. To combat this, FLAVORx Inc, the
flavoring specialists for prescription and over-the-counter
medications, has developed a proven and successful formulation
to convert corticosteroid medications into palatable liquids.
Bethesda, MD (PRWEB) June 1, 2006 - FLAVORx,
Inc, the industry expert in medicinal flavoring, has developed
a unique formulation to combat the extremely bitter and acrid
taste of corticosteroid medications. Prednisolone, the most
common generic form of corticosteroid, can be used to remedy
the symptoms of a myriad of disorders. Its strong anti-inflammatory
effects can be used to treat allergic reactions, breathing
disorders such as asthma and COPD (Chronic Obstructive Pulmonary
Disease), skin conditions, digestive problems, arthritis,
adrenal gland problems, cancer, blood disorders, eye diseases
and multiple sclerosis by decreasing swelling and reducing
activity of the immune system. For children and those who
have difficulty swallowing tablets, prednisolone is available
in an oral liquid. Unfortunately, the extremely unpalatable
taste of this multi-functional medication leads to extremely
poor medicinal compliance, which can result in additional
complication from improper dosing and non-adherence.
In children especially, the bitter taste of corticosteroid
drugs can be enough to warrant refusal of the medication and
in some cases involuntary vomiting, when the drug is simply
too unpleasant to a young palate. In extreme cases children
that require these medications daily have been found to become
nauseous several hours before having to take them just from
psychological anticipation. Studies have shown that upwards
of 20% of children (aged 2-10) experience vomiting after ingesting
oral prednisolone. Frequent or repeated vomiting can lead
to much more severe complications beyond just the sheer horrendous
experience. More importantly, when a child spits up a medication,
there is no certainty as to how much medication has actually
been ingested. The concern thus arises for parents, guardians
and healthcare practitioners as to whether another dose should
be administered, or if in fact, a child would actually be
given too much medication.
In addition, commonly when children refuse or have severe
difficulty swallowing medication, they fail to finish a complete
drug regimen. Parents may feel that the effort required and
strain on the child simply does not outweigh the drug's benefits.
In the case of all medications, non-compliance such as this
can lead to persistent symptoms, and specifically in the case
of prednisolone, abruptly stopping the medication can cause
corticosteroid insufficiency accompanied by nausea, vomiting,
and even shock.
FLAVORx's unique formulation to negate the bitterness of
corticosteroid medications has been taste-approved and stability-tested
to ensure a much more pleasant experience while still maintaining
the complete efficacy of the drug. In addition, to date, FLAVORx
has reported no incidence of vomiting after ingesting prednisolone
flavored with its unique formulation from patients. Combined
with proprietary materials such as the FLAVORx Bitterness
Suppressor and Sweetening Enhancer, flavors such as FLAVORx's
Sour Apple, Raspberry and Grape, successfully mask the bitter
flavor of all oral corticosteroids such as prednisolone and
dexamethasone. Other more palatable corticosteroids such as
trade name Orapred® are commonly more favorable to children,
however, can be quite costly. While on average, having a generic
medication flavored by the pharmacy using the FLAVORx system
costs only $1.88 to $3.00.
To date, FLAVORx has successfully flavored over 52 million
prescriptions without any incidence of complication, decrease
in efficacy or allergic reaction.
For more information, please contact Teresa Chen
at 800.884.5771 extension 234.
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